Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells

Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells

Several classes of immunomodulators are used for treating relapsing-remitting multiple sclerosis (RRMS). Most of these disease-modifying therapies, except teriflunomide, carry the risk of progressive multifocal leukoencephalopathy (PML), a severely debilitating, often fatal virus-induced demyelinati...

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Bibliographic Details
Main Authors: Bethany A. O’Hara, Gretchen V. Gee, Sheila A. Haley, Jenna Morris-Love, Charlotte Nyblade, Chris Nieves, Barbara A. Hanson, Xin Dang, Timothy J. Turner, Jeffrey M. Chavin, Alex Lublin, Igor J. Koralnik, Walter J. Atwood
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
demyelination
glia
autoimmunity
neuroinflammation
choroid plexus
Online Access:https://www.mdpi.com/1422-0067/22/18/9809

Internet

https://www.mdpi.com/1422-0067/22/18/9809

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