Resveratrol exerts antitumor effects by downregulating CD8+CD122+ Tregs in murine hepatocellular carcinoma

Resveratrol exerts antitumor effects by downregulating CD8+CD122+ Tregs in murine hepatocellular carcinoma

CD4+Foxp3+ regulatory T cells (Tregs) in the tumor microenvironment restrain antitumor immunity, resulting in tumor aggression and poor survival in hepatocellular carcinoma (HCC). CD8+CD122+ Tregs have been previously shown to be more potent in immunosuppression than are CD4+Foxp3+ Tregs. Previous s...

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Bibliographic Details
Main Authors: Qunfang Zhang, Haiding Huang, Fang Zheng, Huazhen Liu, Feifei Qiu, Yuchao Chen, Chun-Ling Liang, Zhenhua Dai
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
resveratrol
regulatory t cells
tumor-associated macrophages
tumor microenvironment
hepatocellular carcinoma
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1829346

Internet

http://dx.doi.org/10.1080/2162402X.2020.1829346

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