Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastomaResearch in context

Background: Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood. In this study, we identified the role of exosomal microRNAs (miRNAs) from TMZ-resistant cells as important mediators of chemoresistan...

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Bibliographic Details
Main Authors: Jianxing Yin, Ailiang Zeng, Zhuoran Zhang, Zhumei Shi, Wei Yan, Yongping You
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419301562