Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes

The discovery and development of novel anthelmintic classes is essential to sustain the control of socioeconomically important parasitic worms of humans and animals. With the aim of offering novel, lead-like scaffolds for drug discovery, Compounds Australia released the ‘Open Scaffolds’ collection c...

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Bibliographic Details
Main Authors: Sarah Preston, Yaqing Jiao, Jonathan B. Baell, Jennifer Keiser, Simon Crawford, Anson V. Koehler, Tao Wang, Moana M. Simpson, Ray M. Kaplan, Karla J. Cowley, Kaylene J. Simpson, Andreas Hofmann, Abdul Jabbar, Robin B. Gasser
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320717300398

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http://www.sciencedirect.com/science/article/pii/S2211320717300398

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