Design of a randomized controlled trial to evaluate effectiveness of methotrexate versus prednisone as first-line treatment for pulmonary sarcoidosis: the PREDMETH study

Design of a randomized controlled trial to evaluate effectiveness of methotrexate versus prednisone as first-line treatment for pulmonary sarcoidosis: the PREDMETH study

Abstract Background Treatment of pulmonary sarcoidosis is recommended in case of significant symptoms, impaired or deteriorating lung function. Evidence-based treatment recommendations are limited and largely based on expert opinion. Prednisone is currently the first-choice therapy and leads to shor...

Full description

Bibliographic Details
Main Authors: Vivienne Kahlmann, Montse Janssen Bonás, Catharina C. Moor, Coline H. M. van Moorsel, Mirjam Kool, Raisa Kraaijvanger, Jan C. Grutters, Mayka Overgaauw, Marcel Veltkamp, Marlies S. Wijsenbeek, Collaborating investigators
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Pulmonary Medicine
Subjects:
Sarcoidosis
Prednisone
Methotrexate
Biomarkers
Quality of life
Home monitoring
Online Access:http://link.springer.com/article/10.1186/s12890-020-01290-9

Internet

http://link.springer.com/article/10.1186/s12890-020-01290-9

Similar Items