Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules.

Ligands binding to Toll-like receptor (TLR), interleukin 1 receptor (IL-1R), or IFN-γR1 are known to trigger MyD88-mediated signaling, which activates pro-inflammatory cytokine responses. Recently we reported that staphylococcal enterotoxins (SEA or SEB), which bind to MHC class II molecules on APCs...

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Bibliographic Details
Main Authors: Teri L Kissner, Gordon Ruthel, Shahabuddin Alam, Robert G Ulrich, Stefan Fernandez, Kamal U Saikh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024394?pdf=render