Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter

Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter

Background: Adenoviral gene transfer has been shown to be effective in cardiac myocytes in vitro and in vivo. A major limitation of myocardial gene therapy is the extracardiac transgene expression. Methods: To minimize extracardiac gene expression, we have constructed a tissue-specific promoter for...

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Bibliographic Details
Main Authors: Wolfgang Boecker, Oliver Y. Bernecker, Joseph C. Wu, Xinsheng Zhu, Tomohiro Sawa, Luanda Grazette, Anthony Rosenzweig, Federica del Monte, Ulrich Schmidt, Roger J. Hajjar
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200404103

Internet

https://doi.org/10.1162/15353500200404103

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