The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice

The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice

Trophoblasts are the first cell type to be specified during embryogenesis, and they are essential for placental morphogenesis and function. Trophoblast stem (TS) cells are the progenitor cells for all trophoblast lineages; control of TS cell differentiation into distinct trophoblast subtypes is not...

Full description

Bibliographic Details
Main Authors: Mariyan J. Jeyarajah, Gargi Jaju Bhattad, Dendra M. Hillier, Stephen J. Renaud
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
embryogenesis
blastocyst
transcriptional repression
trophoblast stem cells
trophoblast differentiation
placenta
Online Access:https://www.mdpi.com/2073-4409/9/4/840

Internet

https://www.mdpi.com/2073-4409/9/4/840

Similar Items