E2F/Dp inactivation in fat body cells triggers systemic metabolic changes

E2F/Dp inactivation in fat body cells triggers systemic metabolic changes

The E2F transcription factors play a critical role in controlling cell fate. In Drosophila, the inactivation of E2F in either muscle or fat body results in lethality, suggesting an essential function for E2F in these tissues. However, the cellular and organismal consequences of inactivating E2F in t...

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Bibliographic Details
Main Authors: Maria Paula Zappia, Ana Guarner, Nadia Kellie-Smith, Alice Rogers, Robert Morris, Brandon Nicolay, Myriam Boukhali, Wilhelm Haas, Nicholas J Dyson, Maxim V Frolov
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
e2f/rb pathway
sugar metabolism
trehalose
triglycerides
proteome
Online Access:https://elifesciences.org/articles/67753

Internet

https://elifesciences.org/articles/67753

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