Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Summary: Microglia are ubiquitous central nervous system (CNS)-resident macrophages that maintain homeostasis of neural tissues and protect them from pathogen attacks. Yet, their differentiation in different compartments remains elusive. We performed single-cell RNA-seq to compare microglial subtype...

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Bibliographic Details
Main Authors: Junying Zheng, Wenjuan Ru, Jay R. Adolacion, Michael S. Spurgat, Xin Liu, Subo Yuan, Rommel X. Liang, Jianli Dong, Andrew S. Potter, S Steven Potter, Ken Chen, Rui Chen, Navin Varadarajan, Shao-Jun Tang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Immunology
Developmental Biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001541

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http://www.sciencedirect.com/science/article/pii/S2589004221001541

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