Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain

Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain

Objective: Every cell type is characterized by a specific transcriptional profile together with a unique epigenetic landscape. Reprogramming factors such as Oct4, Klf4, Sox2 and c-Myc enable somatic cells to change their transcriptional profile and convert them to pluripotent cells. Small molecules...

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Bibliographic Details
Main Authors: Sareh Asadi, Samaneh Dehghan, Maryam Hajikaram, Seyed Javad Mowla, Abolhassan Ahmadiani, Mohammad Javan
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2015-01-01
Series:Cell Journal
Subjects:
Oct4
Valproic Acid
Reprogramming
Pluripotency
Small Molecules
Online Access:http://celljournal.org/library/upload/article/af_73655233463245542743233244554322744463234-Sareh%20Asadi-print.pdf

Internet

http://celljournal.org/library/upload/article/af_73655233463245542743233244554322744463234-Sareh%20Asadi-print.pdf

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