Probing the run-on oligomer of activated SgrAI bound to DNA.

Probing the run-on oligomer of activated SgrAI bound to DNA.

SgrAI is a type II restriction endonuclease with an unusual mechanism of activation involving run-on oligomerization. The run-on oligomer is formed from complexes of SgrAI bound to DNA containing its 8 bp primary recognition sequence (uncleaved or cleaved), and also binds (and thereby activates for...

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Bibliographic Details
Main Authors: Santosh Shah, Jonathan Sanchez, Andrew Stewart, Michael M Piperakis, Richard Cosstick, Claire Nichols, Chad K Park, Xin Ma, Vicki Wysocki, Jurate Bitinaite, Nancy C Horton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4399878?pdf=render

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http://europepmc.org/articles/PMC4399878?pdf=render

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