Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease

Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease

Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in...

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Main Authors: Julien Caliez, Marianne Riou, Grégoire Manaud, Morad K. Nakhleh, Marceau Quatredeniers, Catherine Rucker-Martin, Peter Dorfmüller, Florence Lecerf, Maria C. Vinhas, Salam Khatib, Hossam Haick, Sylvia Cohen-Kaminsky, Marc Humbert, David Montani, Frédéric Perros
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894020907884

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https://doi.org/10.1177/2045894020907884

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