Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia

Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia

<p>Abstract</p> <p>Background</p> <p>Although current chemotherapy regimens have remarkably improved the cure rate of pediatric acute promyelocytic leukemia (APL) over the past decade, more than 20% of patients still die of the disease, and the 5-year cumulative inciden...

Full description

Bibliographic Details
Main Authors: Chen Xiao, Zheng Yu-Sheng, Wu Jun, Zhang Xing-Ju, Feng Dan-Dan, Luo Xue-Qun, Zhang Hua, Xu Ling, Chen Yue-Qin
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Molecular Cancer
Subjects:
microRNA
pediatric acute promyelocytic leukemia (APL)
treatment response
drug resistance
Online Access:http://www.molecular-cancer.com/content/10/1/108

Internet

http://www.molecular-cancer.com/content/10/1/108

Similar Items