LncRNA NEAT1 promotes nucleus pulposus cell matrix degradation through regulating Nrf2/ARE axis

LncRNA NEAT1 promotes nucleus pulposus cell matrix degradation through regulating Nrf2/ARE axis

Abstract Background This study aimed to assess the role and mechanism of lncRNA NEAT1 in intervertebral disc degeneration (IVD). Methods LncRNA profile (GSE56081) between IVD and healthy control was downloaded from the Gene Expression Omnibus (GEO) database and analyzes differential lncRNA expressio...

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Bibliographic Details
Main Authors: Cheng Li, Xinjian Ma, Chenfei Ni, Jingyan Xu, Yinfei Xie, Junwei Kan, Xiaoli Wei
Format: Article
Language:English
Published: BMC 2021-01-01
Series:European Journal of Medical Research
Subjects:
LncRNA NEAT1
Intervertebral disc degeneration
Nrf2/ARE signaling pathway
Online Access:https://doi.org/10.1186/s40001-021-00481-2

Internet

https://doi.org/10.1186/s40001-021-00481-2

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