Quinone-amino acid conjugates targeting Leishmania amino acid transporters.

Quinone-amino acid conjugates targeting Leishmania amino acid transporters.

The aim of the present study was to investigate the feasibility of targeting Leishmania transporters via appropriately designed chemical probes. Leishmania donovani, the parasite that causes visceral leishmaniasis, is auxotrophic for arginine and lysine and has specific transporters (LdAAP3 and LdAA...

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Bibliographic Details
Main Authors: Federica Prati, Adele Goldman-Pinkovich, Federica Lizzi, Federica Belluti, Roni Koren, Dan Zilberstein, Maria Laura Bolognesi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177859?pdf=render

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http://europepmc.org/articles/PMC4177859?pdf=render

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