Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers ColitisSummary

Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers ColitisSummary

Background & Aims: Antibiotic (ABx) therapy is associated with increased risk for Crohn’s disease but underlying mechanisms are unknown. We observed high fecal serine protease activity (PA) to be a frequent side effect of ABx therapy. The aim of the present study was to unravel whether this rise...

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Bibliographic Details
Main Authors: Hongsup Yoon, Monika Schaubeck, Ilias Lagkouvardos, Andreas Blesl, Stephanie Heinzlmeir, Hannes Hahne, Thomas Clavel, Suchita Panda, Christina Ludwig, Bernhard Kuster, Chaysavanh Manichanh, Patrizia Kump, Dirk Haller, Gabriele Hörmannsperger
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18300845

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http://www.sciencedirect.com/science/article/pii/S2352345X18300845

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