Transient light-activated gene expression in Chinese hamster ovary cells

Abstract Background Chinese hamster ovary (CHO) cells are widely used for industrial production of biopharmaceuticals. Many genetic, chemical, and environmental approaches have been developed to modulate cellular pathways to improve titers. However, these methods are often irreversible or have off-t...

Full description

Bibliographic Details
Main Authors: Shiaki A. Minami, Priya S. Shah
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Biotechnology
Online Access:https://doi.org/10.1186/s12896-021-00670-1