Docking to a Basic Helix Promotes Specific Phosphorylation by G1-Cdk1

Cyclins are the activators of cyclin-dependent kinase (CDK) complex, but they also act as docking scaffolds for different short linear motifs (SLiMs) in CDK substrates and inhibitors. According to the unified model of CDK function, the cell cycle is coordinated by CDK both via general CDK activity t...

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Bibliographic Details
Main Authors: Ilona Faustova, Kaidi Möll, Ervin Valk, Mart Loog, Mihkel Örd
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/17/9514