Novel C7-Substituted Coumarins as Selective Monoamine Oxidase Inhibitors: Discovery, Synthesis and Theoretical Simulation

There is a continued need to develop new selective human monoamine oxidase (<i>h</i>MAO) inhibitors that could be beneficial for the treatment of neurological diseases. However, <i>h</i>MAOs are closely related with high sequence identity and structural similarity, which hind...

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Bibliographic Details
Main Authors: Dong Wang, Ren-Yuan Hong, Mengyao Guo, Yi Liu, Nianhang Chen, Xun Li, De-Xin Kong
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/21/4003