Functional significance of CD57 expression on human NK cells and relevance to disease

Historically, human NK cells have been identified as CD3-CD56+CD16+/- lymphocytes. More recently it has been established that CD57 expression defines functionally discrete subpopulations of NK cells. On T cells, CD57 expression has been regarded as a marker of terminal differentiation and (perhaps...

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Bibliographic Details
Main Authors: Carolyn M Nielsen, Matthew J White, Martin R Goodier, Eleanor M Riley
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00422/full