Synthesis and Antiviral Bioactivity of Chiral Thioureas Containing Leucine and Phosphonate Moieties

Synthesis and Antiviral Bioactivity of Chiral Thioureas Containing Leucine and Phosphonate Moieties

A series of novel chiral thioureas 3a-n bearing leucine and phosphonate moieties were synthesized in excellent yields. The structures of the compounds were completely characterized by elemental analysis, IR, 1H-, 13C-, 31P- and 19F-NMR spectral data. A half-leaf method was used to determine the in v...

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Bibliographic Details
Main Authors: Jian Wu, Zhencao Wang, Weiming Xu, Pinaki Bhadury, Huitao Fan, Xiangyang Li, Song Yang, Jingzi Liu
Format: Article
Language:English
Published: MDPI AG 2010-07-01
Series:Molecules
Subjects:
chiral thiourea
leucine
phosphonate
antiviral activity
synthesis
Online Access:http://www.mdpi.com/1420-3049/15/8/5112/

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http://www.mdpi.com/1420-3049/15/8/5112/

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