Molecular mechanisms of macrophage Toll-like receptor–Fc receptor synergy [version 1; referees: 2 approved]

Macrophages (MØs) are a key cell type of both the innate and the adaptive immune response and can tailor their response to prevailing conditions. To sense the host’s status, MØs employ two classes of receptors: Toll-like receptors (TLRs), which are sensors for pathogen-derived material, and Fcγ rece...

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Bibliographic Details
Main Authors: Michelle Lennartz, James Drake
Format: Article
Language:English
Published: F1000 Research Ltd 2018-01-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-21/v1