TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon

TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon

Intestinal magnesium (Mg) uptake is essential for systemic Mg homeostasis. Colon cells express the two highly homologous transient receptor potential melastatin type (TRPM) 6 and 7 Mg2+ channels, but their precise function and the consequences of their mutual interaction are not clear. To explore th...

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Bibliographic Details
Main Authors: Francesca Luongo, Giuseppe Pietropaolo, Mathieu Gautier, Isabelle Dhennin-Duthille, Halima Ouadid-Ahidouch, Federica I. Wolf, Valentina Trapani
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Nutrients
Subjects:
cell migration
cell proliferation
intestine
ion imaging
magnesium channel
magnesium homeostasis
MagT1
NS8593
TRPM7
wound healing
Online Access:http://www.mdpi.com/2072-6643/10/6/784

Internet

http://www.mdpi.com/2072-6643/10/6/784

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