Peptide hydrogels – versatile matrices for 3D cell culture in cancer medicine

Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our understanding of cancer biology but have significant limitations in mimicking in vivo conditions such as the tumor microenvironment. In vitro, three-dimensional (3D) cell culture models represent a more accura...

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Bibliographic Details
Main Authors: Peter eWorthington, Darrin John Pochan, Sigrid A Langhans
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00092/full