Genetic Factors in Antiphospholipid Syndrome: Preliminary Experience with Whole Exome Sequencing

Genetic Factors in Antiphospholipid Syndrome: Preliminary Experience with Whole Exome Sequencing

As in many autoimmune diseases, the pathogenesis of the antiphospholipid syndrome (APS) is the result of a complex interplay between predisposing genes and triggering environmental factors, leading to a loss of self-tolerance and immune-mediated tissue damage. While the first genetic studies in APS...

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Bibliographic Details
Main Authors: Alice Barinotti, Massimo Radin, Irene Cecchi, Silvia Grazietta Foddai, Elena Rubini, Dario Roccatello, Savino Sciascia, Elisa Menegatti
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
antiphospholipid syndrome
immunogenetics
whole exome sequencing
network-based approach
antiphospholipid antibodies
thrombosis
Online Access:https://www.mdpi.com/1422-0067/21/24/9551

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https://www.mdpi.com/1422-0067/21/24/9551

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