Caffeine-Cyclodextrin Complexes as Solids: Synthesis, Biological and Physicochemical Characterization

Caffeine-Cyclodextrin Complexes as Solids: Synthesis, Biological and Physicochemical Characterization

Mechanochemical and in-solution synthesis of caffeine complexes with α-, β-, and γ-cyclodextrins was optimized. It was found that short-duration, low-energy cogrinding, and evaporation (instead of freeze-drying) are effective methods for the formation and isolation of these complexes. The products o...

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Bibliographic Details
Main Authors: Sebastian Szmeja, Tomasz Gubica, Andrzej Ostrowski, Aldona Zalewska, Łukasz Szeleszczuk, Katarzyna Zawada, Monika Zielińska-Pisklak, Krzysztof Skowronek, Małgorzata Wiweger
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
caffeine
cyclodextrins
mechanochemical synthesis
analytical methods
toxicity
zebrafish
Online Access:https://www.mdpi.com/1422-0067/22/8/4191

Internet

https://www.mdpi.com/1422-0067/22/8/4191

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