Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool

Hydrocephalus can occur in children alone or in combination with other neurodevelopmental disorders that are often associated with brain overgrowth. Despite the severity of these disorders, the molecular and cellular mechanisms underlying these pathologies and their comorbidity are poorly understood...

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Main Authors: Ksenija Zega, Vukasin M. Jovanovic, Zagorka Vitic, Magdalena Niedzielska, Laura Knaapi, Marin M. Jukic, Juha Partanen, Roland H. Friedel, Roland Lang, Claude Brodski
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Molecular Neuroscience
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Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00372/full