NLRP3 inflammasome activation by Paracoccidioides brasiliensis.

Paracoccidioides brasiliensis is the etiologic agent of paracoccidioidomycosis (PCM), the most prevalent systemic mycosis that is geographically confined to Latin America. The pro-inflammatory cytokine IL-1β that is mainly derived from the activation of the cytoplasmic multiprotein complex inflammas...

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Bibliographic Details
Main Authors: Aldo Henrique Tavares, Kelly Grace Magalhães, Raquel Das Neves Almeida, Rafael Correa, Pedro Henrique Burgel, Anamélia Lorenzetti Bocca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3855149?pdf=render