Construction and Analysis of a ceRNA Network in Cardiac Fibroblast During Fibrosis Based on in vivo and in vitro Data

Construction and Analysis of a ceRNA Network in Cardiac Fibroblast During Fibrosis Based on in vivo and in vitro Data

AimsActivation of cardiac fibroblasts (CF) is crucial to cardiac fibrosis. We constructed a cardiac fibroblast-related competing endogenous RNA (ceRNA) network. Potential functions related to fibrosis of “hub genes” in this ceRNA network were explored.Materials and MethodsThe Gene Expression Omnibus...

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Main Authors: Qing-Yuan Gao, Hai-Feng Zhang, Zhi-Teng Chen, Yue-Wei Li, Shao-Hua Wang, Zhu-Zhi Wen, Yong Xie, Jing-Ting Mai, Jing-Feng Wang, Yang-Xin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
cardiac fibroblast
fibrosis
competing endogenous RNA
ADAM metallopeptidase domain 19
transforming growth factor beta induced
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.503256/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.503256/full

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