Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking.

Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking.

Accumulating evidence underscores the importance of ligand-receptor dynamics in shaping cellular signaling. In the nervous system, growth factor-activated Trk receptor trafficking serves to convey biochemical signaling that underlies fundamental neural functions. Focus has been placed on axonal traf...

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Bibliographic Details
Main Authors: Anke Vermehren-Schmaedick, Wesley Krueger, Thomas Jacob, Damien Ramunno-Johnson, Agnieszka Balkowiec, Keith A Lidke, Tania Q Vu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986401?pdf=render

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http://europepmc.org/articles/PMC3986401?pdf=render

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