Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment

Mitochondrial dysfunction represents a central factor within the pathogenesis of the Alzheimer’s disease (AD) spectrum. We hypothesized that in vivo measurements of lactate (lac), a by-product of glycolysis, would correlate with functional impairment and measures of brain health in a cohort of 15 am...

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Bibliographic Details
Main Authors: Kurt E. Weaver, Todd L. Richards, Rebecca G. Logsdon, Ellen L. McGough, Satoshi Minoshima, Elizabeth H. Aylward, Natalia M. Kleinhans, Thomas J. Grabowski, Susan M. McCurry, Linda Teri
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/610605