Selective localization of Shanks to VGLUT1-positive excitatory synapses in the mouse hippocampus

Selective localization of Shanks to VGLUT1-positive excitatory synapses in the mouse hippocampus

AbstractMembers of the Shank family of multidomain proteins (Shank1, Shank2, and Shank3) are core components of the postsynaptic density (PSD) of excitatory synapses. At synaptic sites Shanks serve as scaffolding molecules that cluster neurotransmitter receptors as well as cell adhesion molecules at...

Full description

Bibliographic Details
Main Authors: Christopher eHeise, Jan eSchroeder, Michael eSchön, Sonja eHalbedl, Dominik eReim, Sarah eWölfle, Michael R. Kreutz, Michael J Schmeisser, Tobias Maria Boeckers
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Hippocampus
Autism Spectrum Disorders
synapse
mossy fibers
VGLUT1
VGLUT2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00106/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00106/full

Similar Items