Modeling-Enabled Characterization of Novel NLRX1 Ligands.

Modeling-Enabled Characterization of Novel NLRX1 Ligands.

Nucleotide-binding domain and leucine-rich repeat containing (NLR) family are intracellular sentinels of cytosolic homeostasis that orchestrate immune and inflammatory responses in infectious and immune-mediated diseases. NLRX1 is a mitochondrial-associated NOD-like receptor involved in the modulati...

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Bibliographic Details
Main Authors: Pinyi Lu, Raquel Hontecillas, Vida Abedi, Shiv Kale, Andrew Leber, Chase Heltzel, Mark Langowski, Victoria Godfrey, Casandra Philipson, Nuria Tubau-Juni, Adria Carbo, Stephen Girardin, Aykut Uren, Josep Bassaganya-Riera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4694766?pdf=render

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http://europepmc.org/articles/PMC4694766?pdf=render

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