Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation

Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation

Objective Dual inhibition of mitogen-activated protein kinase (MAPK) kinase (also known as MEK) and transforming growth factor β (TGFβ) type I receptors by PD0325901 and SB431542, known as R2i has been introduced as a highly efficient approach to the generation of mouse embryonic stem cells (ESC)....

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Bibliographic Details
Main Authors: Azam Samadian, Mahdi Hesaraki, Sepideh Mollamohamadi, Behrouz Asgari, Mehdi Totonchi, Hossein Baharvand
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2018-06-01
Series:Cell Journal
Subjects:
DNA Methylation
MEK Inhibitor
Mouse Embryonic Stem Cells
R2i
TGFβ Inhibitor
Online Access:http://celljournal.org/journal/article/abstract/5482

Internet

http://celljournal.org/journal/article/abstract/5482

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