First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives

Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles in the presence of β-isocupreidine catalyst are reported. The moderate, but promising, enantioselec...

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Bibliographic Details
Main Authors: Fernando Auria-Luna, Eugenia Marqués-López, Raquel P. Herrera
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
chiral base
1,4-dihydropyridine
enantioselective
hydrazone
organocatalysis
Online Access:http://www.mdpi.com/1420-3049/23/10/2692

Internet

http://www.mdpi.com/1420-3049/23/10/2692

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