Comprehensive Profiling of HIV Antibody Evolution

Comprehensive Profiling of HIV Antibody Evolution

Summary: This study evaluates HIV antibody responses and their evolution during the course of HIV infection. A phage display system is used to characterize antibody binding to >3,300 HIV peptides in 57 adults with early- to late-stage infection. We find that the number of unique epitopes targeted...

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Bibliographic Details
Main Authors: Susan H. Eshleman, Oliver Laeyendecker, Kai Kammers, Athena Chen, Mariya V. Sivay, Sanjay Kottapalli, Brandon M. Sie, Tiezheng Yuan, Daniel R. Monaco, Divya Mohan, Daniel Wansley, Tomasz Kula, Charles Morrison, Stephen J. Elledge, Ron Brookmeyer, Ingo Ruczinski, H. Benjamin Larman
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930436X

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http://www.sciencedirect.com/science/article/pii/S221112471930436X

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