Persistence length of human cardiac α-tropomyosin measured by single molecule direct probe microscopy.

α-Tropomyosin (αTm) is the predominant tropomyosin isoform in adult human heart and constitutes a major component in Ca²+-regulated systolic contraction of cardiac muscle. We present here the first direct probe images of WT human cardiac αTm by atomic force microscopy, and quantify its mechanical fl...

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Bibliographic Details
Main Authors: Campion K P Loong, Huan-Xiang Zhou, P Bryant Chase
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3380901?pdf=render