The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma

Hepatic lipid deposition and inflammation represent risk factors for hepatocellular carcinoma (HCC). The mRNA-binding protein tristetraprolin (TTP, gene name <i>ZFP36</i>) has been suggested as a tumor suppressor in several malignancies, but it increases insulin resistance. The aim of th...

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Bibliographic Details
Main Authors: Tarek Kröhler, Sonja M. Kessler, Kevan Hosseini, Markus List, Ahmad Barghash, Sonika Patial, Stephan Laggai, Katja Gemperlein, Johannes Haybaeck, Rolf Müller, Volkhard Helms, Marcel H. Schulz, Jessica Hoppstädter, Perry J. Blackshear, Alexandra K. Kiemer
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
liver cancer
nash
chemoresistance
<i>neat1</i>
hepg2
huh7
bcl2
myc
vegfa
flow cytometry
Online Access:https://www.mdpi.com/2072-6694/11/11/1754

Internet

https://www.mdpi.com/2072-6694/11/11/1754

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