Evolution of human longevity uncoupled from caloric restriction mechanisms.

Caloric restriction (CR) and chemical agents, such as resveratrol and rapamycin that partially mimic the CR effect, can delay morbidity and mortality across a broad range of species. In humans, however, the effects of CR or other life-extending agents have not yet been investigated systematically. H...

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Bibliographic Details
Main Authors: Guodong Zhao, Song Guo, Mehmet Somel, Philipp Khaitovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882206?pdf=render