Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead.

Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead.

Epidemiologic studies are reporting associations between lead exposure and human cancers. A polymorphism in the 5-aminolevulinic acid dehydratase (ALAD) gene affects lead toxicokinetics and may modify the adverse effects of lead.The objective of this study was to evaluate single-nucleotide polymorph...

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Bibliographic Details
Main Authors: Dana M van Bemmel, Paolo Boffetta, Linda M Liao, Sonja I Berndt, Idan Menashe, Meredith Yeager, Stephen Chanock, Sara Karami, David Zaridze, Vsevolod Matteev, Vladimir Janout, Hellena Kollarova, Vladimir Bencko, Marie Navratilova, Neonilia Szeszenia-Dabrowska, Dana Mates, Alena Slamova, Nathaniel Rothman, Summer S Han, Philip S Rosenberg, Paul Brennan, Wong-Ho Chow, Lee E Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3140467?pdf=render

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http://europepmc.org/articles/PMC3140467?pdf=render

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