Convalescent Plasmodium falciparum-specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure

Convalescent Plasmodium falciparum-specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure

Abstract Background Antibody immunity is thought to be essential to prevent severe Plasmodium falciparum infection, but the exact correlates of protection are unknown. Over time, children in endemic areas acquire non-sterile immunity to malaria that correlates with development of antibodies to meroz...

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Bibliographic Details
Main Authors: Anne Kessler, Joseph J. Campo, Visopo Harawa, Wilson L. Mandala, Stephen J. Rogerson, Wenzhu B. Mowrey, Karl B. Seydel, Kami Kim
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Antibody
Protein microarray
Cerebral malaria
Uncomplicated malaria
PfEMP1
Online Access:http://link.springer.com/article/10.1186/s12936-018-2323-4

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http://link.springer.com/article/10.1186/s12936-018-2323-4

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