Remission Induced by TNF Inhibitors Plus Methotrexate is Associated With Changes in Peripheral Naïve B Cells in Patients With Rheumatoid Arthritis

Remission Induced by TNF Inhibitors Plus Methotrexate is Associated With Changes in Peripheral Naïve B Cells in Patients With Rheumatoid Arthritis

Biological therapies, such as TNF inhibitors (TNFi), are increasing remission (REM) rates in rheumatoid arthritis (RA) patients, although these are still limited. The aim of our study was to analyze changes in the profile of peripheral blood mononuclear cells (PBMC) in patients with RA treated with...

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Bibliographic Details
Main Authors: Borja Hernández-Breijo, Chamaida Plasencia-Rodríguez, Victoria Navarro-Compán, Carlota García-Hoz, Israel Nieto-Gañán, Cristina Sobrino, Javier Bachiller-Corral, Mariana Díaz-Almirón, Ana Martínez-Feito, Teresa Jurado, Paloma Lapuente-Suanzes, Gema Bonilla, Cristina Pijoán-Moratalla, Garbiñe Roy, Mónica Vázquez-Díaz, Alejandro Balsa, Luisa M. Villar, Dora Pascual-Salcedo, Eulalia Rodríguez-Martín
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
autoimmunity
B cells
remission
TNF inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.683990/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.683990/full

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