The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site.

In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally...

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Bibliographic Details
Main Authors: Anna Babakhanyan, Rose G F Leke, Ali Salanti, Naveen Bobbili, Philomina Gwanmesia, Robert J I Leke, Isabella A Quakyi, John J Chen, Diane Wallace Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913775?pdf=render