Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation

Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation

Abstract Background Genetic factors may influence an individual’s sensitivity to ionising radiation and therefore modify his/her risk of developing papillary thyroid carcinoma (PTC). Previously, we reported that common single nucleotide polymorphisms (SNPs) within the DNA damage recognition gene ATM...

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Bibliographic Details
Main Authors: Christine Lonjou, Francesca Damiola, Monika Moissonnier, Geoffroy Durand, Irina Malakhova, Vladimir Masyakin, Florence Le Calvez-Kelm, Elisabeth Cardis, Graham Byrnes, Ausrele Kesminiene, Fabienne Lesueur
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cancer
Subjects:
Papillary thyroid carcinoma
Radiation-induced cancer
Genetic susceptibility
DNA repair
MGMT
Online Access:http://link.springer.com/article/10.1186/s12885-017-3314-5

Internet

http://link.springer.com/article/10.1186/s12885-017-3314-5

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