Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice

People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role of circulating FGF-2 in the pathogenesis of chi...

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Bibliographic Details
Main Authors: Jharna R. Das, Marina Jerebtsova, Pingtao Tang, Jinliang Li, Jing Yu, Patricio E. Ray
Format: Article
Language:English
Published: The Company of Biologists 2021-07-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/7/dmm048980