The Imbalance of Circulating Follicular T Helper Cell Subsets in Primary Sjögren’s Syndrome Associates With Serological Alterations and Abnormal B-Cell Distribution

The Imbalance of Circulating Follicular T Helper Cell Subsets in Primary Sjögren’s Syndrome Associates With Serological Alterations and Abnormal B-Cell Distribution

Since B-cell hyperactivity and pathologic antibody response are key features in the immunopathogenesis of primary Sjögren’s syndrome (pSS), the role of follicular T helper (TFH) cells as efficient helpers in the survival and differentiation of B cells has emerged. Our aim was to investigate whether...

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Bibliographic Details
Main Authors: Krisztina Szabó, Ilona Jámbor, Antónia Szántó, Ildikó Fanny Horváth, Tünde Tarr, Britt Nakken, Peter Szodoray, Gábor Papp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
follicular T helper cell
follicular regulatory T cell
B cell
chemokine receptors
primary Sjögren’s syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.639975/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.639975/full

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