Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes.

Exosomes are secreted organelles that have the same topology as the cell and bud outward (outward is defined as away from the cytoplasm) from endosome membranes or endosome-like domains of plasma membrane. Here we describe an exosomal protein-sorting pathway in Jurkat T cells that selects cargo prot...

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Bibliographic Details
Main Authors: Yi Fang, Ning Wu, Xin Gan, Wanhua Yan, James C Morrell, Stephen J Gould
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1885833?pdf=render