Chemoresponse of de novo Acute Myeloid Leukemia to “7+3” Induction can Be Predicted by c-Myc-facilitated Cytogenetics

Background: Identifying patients with de novo acute myeloid leukemia (AML) who will probably respond to the “7 + 3” induction regimen remains an unsolved clinical challenge. This study aimed to identify whether c-Myc could facilitate cytogenetics to predict a “7 + 3” induction chemoresponse in de no...

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Main Authors: Tzu-Hung Hsiao, Ren Ching Wang, Tsai-Jung Lu, Chien-Hung Shih, Yu-Chen Su, Jia-Rong Tsai, Pei-Pei Jhan, Cai-Sian Lia, Han-Ni Chuang, Kuang-Hsi Chang, Chieh-Lin Teng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.649267/full