BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation

Summary: The epithelial compartment of the mammary gland contains basal and luminal cell lineages, as well as stem and progenitor cells that reside upstream in the differentiation hierarchy. Stem and progenitor cell differentiation is regulated to maintain adult tissue and mediate expansion during p...

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Bibliographic Details
Main Authors: Daniel H. Miller, Dexter X. Jin, Ethan S. Sokol, Janel R. Cabrera, Daphne A. Superville, Rebecca A. Gorelov, Charlotte Kuperwasser, Piyush B. Gupta
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300626